EFFECTIVENESS OF ACUPUNCTURAL APPROACH BASED ON QI AND XUE REGULATION IN TRANSFORMING MODERN HEALTH SYSTEMS FOR PAIN AND CHRONIC DISEASE MANAGEMENT
DOI:
https://doi.org/10.62710/37k7zh56Keywords:
Acupuncture, Chronic Pain, Modern Health System, Qi, XueAbstract
Chronic pain is a health problem that can reduce quality of life and increase dependence on analgesic therapy. Acupuncture based on the regulation of Qi and Xue may serve as a complementary approach for chronic pain management; however, its clinical effectiveness and economic implications require measurable evaluation. This study aimed to analyze the effectiveness of acupuncture based on Qi and Xue regulation in reducing pain intensity, improving quality of life, decreasing analgesic use, influencing physiological parameters, and assessing cost-effectiveness among adults with chronic pain. A quasi-experimental design was conducted involving 80 adults aged 18–70 years with chronic pain lasting ≥3 months. Participants were divided into an intervention group (n=40) receiving acupuncture and a control group (n=40) receiving conventional treatment. Data were analyzed using paired t-tests, ANCOVA, Cohen’s d, and incremental cost-effectiveness ratio (ICER). The intervention group showed a reduction in VAS/NRS pain scores from 6.73 at baseline to 3.31 at week 8, compared with a 1.14-point reduction in the control group. The adjusted between-group difference was statistically significant (p<0.001), with a very large effect size (Cohen’s d=3.59). WHOQOL-BREF scores increased by 18.52 points in the intervention group versus 5.96 points in the control group (d=3.33). Analgesic use decreased by 413.73 mg and 108.83 mg, respectively (d=2.60). Acupuncture based on Qi and Xue regulation demonstrated greater clinical effectiveness than conventional treatment and has potential as an evidence-based complementary therapy for chronic pain management.
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Al, M. S. E. T., Suzuki, M., Takahashi, Y., Inoue, D., Kitajima, T., Maekura, T., Miki, K., Ikeoka, K., Konishi, M., Maekura, R., & Fukui, M. (2025). Effectiveness of a long-term acupuncture treatment in patients with COPD: A randomised controlled trial. ERJ Open Research, 11. https://doi.org/10.1183/23120541.00668-2024
Avery, N., McNeilage, A. G., Stanaway, F., Ashton-James, C. E., Blyth, F. M., Martin, R., Gholamrezaei, A., & Glare, P. (2022). Efficacy of interventions to reduce long-term opioid treatment for chronic non-cancer pain: Systematic review and meta-analysis. BMJ, 377, Article e066375. https://doi.org/10.1136/bmj-2021-066375
Cardoso, R. F., Cristina, A., Lacerda, R., Lima, V. P., Fr, L., Oliveira, F. De, Fr, S., Oliveira, F. De, Paula, R., Leiber, C., Dietrich, L., S., C. De, Mendonça, V. A., & Taiar, R. (2022). Efficacy of acupuncture on quality of life, functional performance, dyspnea, and pulmonary function in patients with chronic obstructive pulmonary disease: Protocol for a randomized clinical trial. Clinical Medicine, 11, Article 3048.
Essex, H., Parrott, S., Atkin, K., Ballard, K., Bland, M., Eldred, J., Hewitt, C., Hopton, A., Keding, A., Lansdown, H., Richmond, S., Tilbrook, H., Torgerson, D., Watt, I., Wenham, A., Woodman, J., & Macpherson, H. (2017). An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS). PLOS ONE, 12(6), Article e0178918. https://doi.org/10.1371/journal.pone.0178918
Gepp, R., Gushikem, A., & Felipe, R. (2026). Neuropathic pain and quality of life: A cross-sectional study in brachial plexus injury. Journal of Pain Research, 19, 1–11. https://doi.org/10.2147/JPR.S571035
Hou, Z., Tian, J., Jin, Y., & Yu, H. (2025). Three-needle of regulating the mind combined with umbilical needle intervention for cervical vertigo with deficiency of qi and blood: A study protocol for a randomized controlled trial. Frontiers in Neurology. https://doi.org/10.3389/fneur.2025.1476596
Huang, L., Yang, S., Xu, G., Luo, Q., Yang, C., Tian, H., Liu, Y., Zhou, Z., Huang, F., Gong, S., Li, Q., Yu, X., Chen, M., Huang, D., Liu, Y., Tang, J., Zhang, R., Sun, X., Lu, G., … Chen, J. (2024). Efficacy of acupuncture as an adjunctive treatment to patients with stable COPD: A multicenter, randomized, sham-controlled trial protocol. BMC Complementary Medicine and Therapies, 24, Article 114. https://doi.org/10.1186/s12906-024-04412-6
Hyun, E., & Kim, N. (2023). Economic evaluation of acupuncture as an adjunctive treatment with usual care for mild-to-moderate knee osteoarthritis: A Markov model-based analysis. Integrative Medicine Research, 12, Article 100982. https://doi.org/10.1016/j.imr.2023.100982
James, L. E., Welton-Mitchell, C., Noel, J. R., & James, S. (2020). Integrating mental health and disaster preparedness in intervention: A randomized controlled trial with earthquake- and flood-affected communities in Haiti. Psychological Medicine, 342–352.
Li, M.-T., Li, B., Zhao, Q.-Y., Wang, X., Zhang, H.-L., Wang, L., Wang, W., & Liu, Z. (2024). Effect of acupuncture on quality of life in atrial fibrillation: Study protocol for a randomised controlled trial. BMJ Open, 14, Article e087460. https://doi.org/10.1136/bmjopen-2024-087460
Skevington, S. M., & Epton, T. (2018). How will the sustainable development goals deliver changes in well-being? A systematic review and meta-analysis to investigate whether WHOQOL-BREF scores respond to change. BMJ Global Health, 3, Article e000609. https://doi.org/10.1136/bmjgh-2017-000609
Skonnord, T., Fetveit, A., Skjeie, H., Brekke, M., Grotle, M., Klovning, A., & Aas, E. (2022). Cost-effectiveness analysis of acupuncture compared with usual care for acute non-specific low back pain: Secondary analysis of a randomised controlled trial. Acupuncture in Medicine, 40(2), 123–132. https://doi.org/10.1177/09645284211055747
Wang, Z., Jiang, B., Wang, X., Li, Z., Wang, D., Xue, H., Wang, D., Wang, Z., Jiang, B., Wang, X., & Li, Z. (2023). Relationship between physical activity and individual mental health after traumatic events: A systematic review. European Journal of Psychotraumatology, 14(2), Article 2205667. https://doi.org/10.1080/20008066.2023.2205667
Welton-Mitchell, C., James, L. E., Khanal, S. N., & James, A. S. (2018). An integrated approach to mental health and disaster preparedness: A cluster comparison with earthquake-affected communities in Nepal. BMC Psychiatry, 18, Article 296.
Widiyasningsi, R., Putra, L. E. M., Farida, A., Wati, R., & Rianti, E. D. D. (2026). Pemberian terapi akupunktur pada nyeri otot di regio extremitas inferior. Indonesian Journal of Community Empowerment, 3(1), 109–118. https://doi.org/10.62335
Wulandari, M., & Prihatono, A. (2024). Peran akupunktur dalam mengatasi nyeri lutut pada kasus osteoartritis melalui penurunan sitokin IL-6. Publication of Health Data, 1(2), 24–36.
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